Allan D. Levi, M.D., Ph.D., FACS
- Neurological Surgery
Minimally Invasive Spine Surgery
Peripheral Nerve Surgery
Spinal Cord Tumors
Complex Spinal Surgery- Cervical, Thoracic, Lumbar
Disorders and Disease
Degenerative Disc Disease
Reconstructive Spinal Surgery
Spinal Cord Trauma
- American Board of Neurological Surgery
- Chairman of Neurosurgery, University of Miami MILLER School of Medicine Service Chief of Neurosurgery, Jackson Memorial Hospital
- Chief of Neurosurgery, Jackson Memorial Hospital
- Professor & Chairman of Neurological Surgery Chief of Service, JMH
- Professor, Departments of Neurological Surgery, Orthopedics, and Rehabilitation Medicine
Cellular Transplantation, Spinal Cord Injury, Peripheral Nerve Injury, Hypothermia, Stem Cells My research interests have focused on developing cellular transplantation strategies to repair injuries within both the human central and peripheral nervous system. Schwann cells are the principal support cells with the peripheral nervous system and have the capacity to promote regeneration of central nervous system neurons as well as remyelinate central axons which have lost their insulation. I have focused much of my previous research efforts in furthering our understanding of the biology of human Schwann cells which have been isolated using cell culture techniques. The results of these studies have demonstrated that human Schwann cells have the capacity to form myelin after transplantation within immune deficient rodent models and that their numbers can be significantly increased with addition of growth factors. My current research interests involve serving as (1) PI on intravascular hypothermia after human cervical spinal cord injury (2) co-PI on the FDA approved trial of “The Safety of Autologous Human Schwann Cells in Subjects with Sub-acute Spinal Cord Injury (SCI)” and (3) PI on the clinical development and characterization of the use of autologous human Scwhann cells for peripheral nerve injuries with a lengthy gap to promote peripheral nerve regeneration (4) Site PI of a Phase II Proof-of-Concept Study of the Safety and Efficacy of HuCNS-Stem Cell Transplantation in Cervical Spinal Cord Injury
Top Doctors (Castle Connolly)
Elected Member of the American Academy of Neurological Surgery
Elected Member of the Senior Neurosurgical Society
Roberto C. Heros - Best Resident Teacher Award in Neurosurgery
1995 Spine Fellowship
Barrow Neurological Institute
University of Miami
1987 Neurosurgery Residency
University of Toronto
University of Ottawa
University of Ottawa
Board-certified in neurological surgery, Dr. Levi is an internationally renowned clinical specialist in the treatment of numerous spinal disorders including degenerative spine diseases, spinal trauma, rheumatoid arthritis, tumors, Chiari malformations, and syrinxes. He offers the latest intraoperative technologies including complex spinal instrumentation, artificial cervical discs, spinal cord monitoring and minimally invasive spine surgery. He also has a keen interest in peripheral nerve disorders and treats patients with nerve entrapments, tumors and trauma.
In the area of neuroscience research, he has published extensively on the use of hypothermia after spinal cord injury and the use of human Schwann cells as a biological tool in the repair of peripheral nerve and spinal cord injury. His innovative and successful research program seeks to continually move the field of neurological surgery forward, finding novel treatments that can incrementally improve the lives of patients living with spinal cord injury. His research focuses on developing cellular transplantation strategies to repair injuries within the central and peripheral nervous systems. Currently serving as principal and co-principal investigator on several FDA registered clinical trials studying intravascular hypothermia after human cervical spinal cord injury, cellular transplantation of human Schwann cells for spinal cord injury and stem cell transplantation for cervical spinal cord injury.
Dr. Levi has authored two books, dozens of book chapters and more than 120 peer-reviewed journal articles. He is a Fellow of the American College of Surgeons and an elected member of two of the most prestigious neurosurgical societies, the American Academy of Neurosurgery and the Senior Society of Neurological Surgeons. He has served as national course director for the oral board preparatory course for the American Association of Neurological Surgeons since 2007.
A Canadian native, Dr. Levi received a Bachelor of Science degree in biology and medical science (research), and a medical degree from the University of Ottawa and a Ph.D. in neuroscience studying human Schwann cell biology from the University of Miami School of Medicine. He completed a neurological surgery residency at the University of Toronto Faculty of Medicine and a spine fellowship at the Barrow Neurological Institute in Phoenix, Arizona.